Turnstone Biologics (NASDAQ:TSBX – Get Free Report) and Protalix BioTherapeutics (NYSE:PLX – Get Free Report) are both small-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their risk, valuation, institutional ownership, earnings, analyst recommendations, dividends and profitability.
Institutional & Insider Ownership
52.5% of Turnstone Biologics shares are owned by institutional investors. Comparatively, 16.5% of Protalix BioTherapeutics shares are owned by institutional investors. 32.1% of Turnstone Biologics shares are owned by company insiders. Comparatively, 6.3% of Protalix BioTherapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.
Profitability
This table compares Turnstone Biologics and Protalix BioTherapeutics’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Turnstone Biologics | N/A | -85.18% | -72.25% |
| Protalix BioTherapeutics | -38.62% | -45.15% | -16.63% |
Risk & Volatility
Analyst Recommendations
This is a summary of current ratings and target prices for Turnstone Biologics and Protalix BioTherapeutics, as provided by MarketBeat.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Turnstone Biologics | 0 | 1 | 1 | 0 | 2.50 |
| Protalix BioTherapeutics | 0 | 0 | 1 | 0 | 3.00 |
Turnstone Biologics currently has a consensus price target of $2.13, suggesting a potential upside of 334.47%. Protalix BioTherapeutics has a consensus price target of $10.00, suggesting a potential upside of 817.43%. Given Protalix BioTherapeutics’ stronger consensus rating and higher possible upside, analysts plainly believe Protalix BioTherapeutics is more favorable than Turnstone Biologics.
Earnings & Valuation
This table compares Turnstone Biologics and Protalix BioTherapeutics”s revenue, earnings per share and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Turnstone Biologics | $19.31 million | 0.59 | -$55.20 million | ($10.14) | -0.05 |
| Protalix BioTherapeutics | $65.49 million | 1.22 | $8.31 million | ($0.20) | -5.45 |
Protalix BioTherapeutics has higher revenue and earnings than Turnstone Biologics. Protalix BioTherapeutics is trading at a lower price-to-earnings ratio than Turnstone Biologics, indicating that it is currently the more affordable of the two stocks.
Summary
Protalix BioTherapeutics beats Turnstone Biologics on 8 of the 13 factors compared between the two stocks.
About Turnstone Biologics
Turnstone Biologics Corp., a clinical stage biotechnology company, focuses on developing medicines to treat and cure patients with solid tumors. The company's lead product includes TIDAL-01 that is in Phase 1 clinical trials for the treatment of breast cancer, colorectal cancer, head and neck cancer and uveal melanoma, as well as an investigator sponsored trials to treat colorectal cancer, head and neck cancer, and cutaneous and non-cutaneous melanomas. It is also developing TIDAL-02, which is in preclinical development for the treatment of solid tumors. The company was founded in 2014 and is based in LA Jolla, California.
About Protalix BioTherapeutics
Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on its proprietary ProCellEx plant cell-based protein expression system in the United States, Australia, Canada, Israel, Brazil, Russia, Turkey, and internationally. The company offers Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell-expressed recombinant PEGylated Uricase which is in Phase I trial for the treatment of gout; and PRX-119, a plant cell-expressed PEGylated recombinant human DNase I product candidate that is in preclinical phase for the treatment of NETs-related diseases. The company has agreements and partnerships with Pfizer; Fundação Oswaldo Cruz; and Chiesi Farmaceutici S.p.A. The company was incorporated in 1993 and is headquartered in Karmiel, Israel. Protalix BioTherapeutics, Inc. is a subsidiary of Protalix Ltd.
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